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Does lindane (gamma-hexachlorocyclohexane) increase the rapid delayed rectifier outward K(+) current (I(Kr)) in frog atrial myocytes?

BACKGROUND: The effects of lindane, a gamma-isomer of hexachlorocyclohexane, were studied on transmembrane potentials and currents of frog atrial heart muscle using intracellular microelectrodes and the whole cell voltage-clamp technique. RESULTS: Lindane (0.34 microM to 6.8 microM) dose-dependently...

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Autors principals: Sauviat, Martin-Pierre, Colas, Anthony, Pages, Nicole
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC117783/
https://ncbi.nlm.nih.gov/pubmed/12106504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2210-2-15
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