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Human cathepsin B1. Inhibition by α(2)-macroglobulin and other serum proteins

1. Normal human serum was found to inhibit human cathepsin B1. 2. The major inhibitor present in serum was purified and identified as α(2)-macroglobulin. 3. α(2)-Macroglobulin was found to bind cathepsin B1 in an approximately 1:1 molar ratio. When bound, the enzyme retained about 50% of its proteol...

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Detalhes bibliográficos
Main Authors: Starkey, Phyllis M., Barrett, Alan J.
Formato: Artigo
Idioma:Inglês
Publicado em: 1973
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1177542/
https://ncbi.nlm.nih.gov/pubmed/4198623
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