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Human ISG15 conjugation targets both IFN-induced and constitutively expressed proteins functioning in diverse cellular pathways
IFN-α/β plays an essential role in innate immunity against viral and bacterial infection. Among the proteins induced by IFN-α/β are the ubiquitin-like ISG15 protein and its E1- (Ube1L) and E2- (UbcH8) conjugating enzymes, leading to the conjugation of ISG15 to cellular proteins. It is likely that IS...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1177427/ https://ncbi.nlm.nih.gov/pubmed/16009940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504754102 |
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