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An increase in telomere sister chromatid exchange in murine embryonic stem cells possessing critically shortened telomeres
Telomerase deficiency leads to a progressive loss of telomeric DNA that eventually triggers cell apoptosis in human primary cells during prolonged growth in culture. Rare survivors can maintain telomere length through either activation of telomerase or recombination-based telomere lengthening, and t...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1177420/ https://ncbi.nlm.nih.gov/pubmed/16000404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504635102 |
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