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Assembly of immunoglobulin M. Blocked thiol groups of intracellular 7S subunits

We have shown previously that immunoglobulin M (IgM) is present within IgM-forming cells mainly in its 7S subunit form (IgMs), whereas only fully assembled IgM pentamers are secreted. There is no spontaneous polymerization of intracellular IgMs in cell lysates, suggesting that the 7S subunits had bl...

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Detalhes bibliográficos
Main Authors: Askonas, Brigitte A., Parkhouse, R. M. E.
Formato: Artigo
Idioma:Inglês
Publicado em: 1971
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1177004/
https://ncbi.nlm.nih.gov/pubmed/5126912
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