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The pathway of pepsin-catalysed transpeptidation. Evidence for the reactive species being the anion of the acceptor molecule
1. The inhibition of pepsin-catalysed hydrolysis of N-acetyl-l-phenylalanyl-l-phenylalanylglycine by the acyl product and product analogues was studied at pH4.3. 2. The acyl product, N-acetyl-l-phenylalanine, gives rise to linear competitive inhibition at pH4.3, whereas at pH2.1 it shows linear non-...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1971
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1176769/ https://ncbi.nlm.nih.gov/pubmed/4940609 |
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