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Pink-eyed Dilution Protein Controls the Processing of Tyrosinase

The processing of tyrosinase, which catalyzes the limiting reaction in melanin synthesis, was investigated in melan-p1 melanocytes, which are null at the p locus. Endoglycosidase H digestion showed that a significant fraction of tyrosinase was retained in the endoplasmic reticulum. This retention co...

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Autori principali: Chen, Kun, Manga, Prashiela, Orlow, Seth J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC117617/
https://ncbi.nlm.nih.gov/pubmed/12058062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.02-02-0022.
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