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Blockade by calcium antagonists of chemical excitation and sensitization of polymodal nociceptors in the cat's cornea.

1. The possibility that a modified Ca2+ channel mediates chemical and thermal excitation of nociceptors was examined in single polymodal nociceptive fibres of the cat's cornea. 2. Ca2+ channel blockers cadmium (2.5 mM) and diltiazem (1 mM), and high external [Ca2+] (40 mM), markedly reduced noc...

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Autors principals: Pozo, M A, Gallego, R, Gallar, J, Belmonte, C
Format: Artigo
Idioma:Inglês
Publicat: 1992
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1176117/
https://ncbi.nlm.nih.gov/pubmed/1331422
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