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ER-Golgi Traffic Is a Prerequisite for Efficient ER Degradation

Protein quality control is an essential function of the endoplasmic reticulum. Misfolded proteins unable to acquire their native conformation are retained in the endoplasmic reticulum, retro-translocated back into the cytosol, and degraded via the ubiquitin-proteasome system. We show that efficient...

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Hlavní autoři: Taxis, Christof, Vogel, Frank, Wolf, Dieter H.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC117605/
https://ncbi.nlm.nih.gov/pubmed/12058050
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