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The Bloom's syndrome helicase promotes the annealing of complementary single-stranded DNA
The product of the gene mutated in Bloom's syndrome, BLM, is a 3′–5′ DNA helicase belonging to the highly conserved RecQ family. In addition to a conventional DNA strand separation activity, BLM catalyzes both the disruption of non-B-form DNA, such as G-quadruplexes, and the branch migration of...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1176015/ https://ncbi.nlm.nih.gov/pubmed/16024743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki712 |
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