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The Bloom's syndrome helicase promotes the annealing of complementary single-stranded DNA

The product of the gene mutated in Bloom's syndrome, BLM, is a 3′–5′ DNA helicase belonging to the highly conserved RecQ family. In addition to a conventional DNA strand separation activity, BLM catalyzes both the disruption of non-B-form DNA, such as G-quadruplexes, and the branch migration of...

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Hlavní autoři: Cheok, Chit Fang, Wu, Leonard, Garcia, Patrick L., Janscak, Pavel, Hickson, Ian D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1176015/
https://ncbi.nlm.nih.gov/pubmed/16024743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki712
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