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Hepatocellular carcinoma and the penetrance of HFE C282Y mutations: a cross sectional study

BACKGROUND: Although most patients with hereditary haemochromatosis have HFE C282Y mutations, the lifetime risk to HFE C282Y homozygotes of developing fatal diseases such as hepatocellular carcinoma is uncertain. We have carried out a cross-sectional study to determine the proportion of diagnosed he...

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Detalhes bibliográficos
Main Authors: Willis, Gavin, Bardsley, Vicky, Fellows, Ian W, Lonsdale, Ray, Wimperis, Jennie Z, Jennings, Barbara A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1175847/
https://ncbi.nlm.nih.gov/pubmed/15929796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-5-17
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