Role of basal release of nitric oxide on coronary flow and mechanical performance of the isolated rat heart.

1. The role of nitric oxide (NO) in the regulation of coronary flow and mechanical function was studied in isolated working rat hearts. 2. The inhibition of basal release of NO by L-Ng-monomethylarginine (L-NMMA; 500 microM), a specific inhibitor of its synthesis, induced a reduction of coronary flo...

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Detalhes bibliográficos
Main Authors: Amrani, M, O'Shea, J, Allen, N J, Harding, S E, Jayakumar, J, Pepper, J R, Moncada, S, Yacoub, M H
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1175706/
https://ncbi.nlm.nih.gov/pubmed/1293292
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