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Mechanisms of caffeine-induced contraction and relaxation of rat aortic smooth muscle.

1. Using front-surface fluorimetry and Fura-2, we determined the effects of caffeine on cytosolic calcium concentration ([Ca2+]i) and on tension of strips of the rat thoracic aorta. We also determined the effects of caffeine on 45Ca2+ influx into the strips. The objective was to elucidate the mechan...

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Detalhes bibliográficos
Main Authors: Watanabe, C, Yamamoto, H, Hirano, K, Kobayashi, S, Kanaide, H
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1175678/
https://ncbi.nlm.nih.gov/pubmed/1338095
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