Evidence of positive selection acting at the human dopamine receptor D4 gene locus

Associations have been reported of the seven-repeat (7R) allele of the human dopamine receptor D4 (DRD4) gene with both attention-deficit/hyperactivity disorder and the personality trait of novelty seeking. This polymorphism occurs in a 48-bp tandem repeat in the coding region of DRD4, with the most...

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Détails bibliographiques
Auteurs principaux: Ding, Yuan-Chun, Chi, Han-Chang, Grady, Deborah L., Morishima, Atsuyuki, Kidd, Judith R., Kidd, Kenneth K., Flodman, Pamela, Spence, M. Anne, Schuck, Sabrina, Swanson, James M., Zhang, Ya-Ping, Moyzis, Robert K.
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 2002
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC117557/
https://ncbi.nlm.nih.gov/pubmed/11756666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.012464099
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