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The mechanism by which cytoplasmic protons inhibit the sodium-calcium exchanger in guinea-pig heart cells.

1. We recorded cardiac sodium-calcium exchange current (INa-Ca) in giant excised membrane patches obtained from cardiac myocytes of the adult guinea-pig. 2. Rapid changes in ion concentrations on the cytoplasmic side of the excised membrane patch were produced using a modified oil-gate bath. 3. Sodi...

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Detalhes bibliográficos
Main Authors: Doering, A E, Lederer, W J
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1175488/
https://ncbi.nlm.nih.gov/pubmed/8410703
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