Proton currents in human granulocytes: regulation by membrane potential and intracellular pH.

1. To determine whether conductive pathways contribute to the H+ efflux from granulocytes, we used the whole-cell patch-clamp technique combined with microfluorimetric determinations of cytosolic pH (pHi) in single, dimethylsulphoxide-differentiated HL-60 cells. 2. In voltage-clamp mode, depolarizat...

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Autores principales: Demaurex, N, Grinstein, S, Jaconi, M, Schlegel, W, Lew, D P, Krause, K H
Formato: Artigo
Lenguaje:Inglês
Publicado: 1993
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1175481/
https://ncbi.nlm.nih.gov/pubmed/7692041
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