Exploring the folding landscape of a structured RNA

Structured RNAs achieve their active states by traversing complex, multidimensional energetic landscapes. Here we probe the folding landscape of the Tetrahymena ribozyme by using a powerful approach: the folding of single ribozyme molecules is followed beginning from distinct regions of the folding...

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Bibliographic Details
Main Authors: Russell, Rick, Zhuang, Xiaowei, Babcock, Hazen P., Millett, Ian S., Doniach, Sebastian, Chu, Steven, Herschlag, Daniel
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2002
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC117531/
https://ncbi.nlm.nih.gov/pubmed/11756689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.221593598
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