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Signalling pathway involved in nitric oxide synthase type II activation in chondrocytes: synergistic effect of leptin with interleukin-1

The objective of the present study was to investigate the effect of leptin, alone or in combination with IL-1, on nitric oxide synthase (NOS) type II activity in vitro in human primary chondrocytes, in the mouse chondrogenic ATDC5 cell line, and in mature and hypertrophic ATDC5 differentiated chondr...

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Autori principali: Otero, Miguel, Lago, Rocío, Lago, Francisca, Reino, Juan Jesús Gomez, Gualillo, Oreste
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1174950/
https://ncbi.nlm.nih.gov/pubmed/15899045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1708
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