The utility of pathway selective estrogen receptor ligands that inhibit nuclear factor-κB transcriptional activity in models of rheumatoid arthritis

Rheumatoid arthritis (RA) is a chronic inflammatory disease that produces synovial proliferation and joint erosions. The pathologic lesions of RA are driven through the production of inflammatory mediators in the synovium mediated, in part, by the transcription factor NF-κB. We have identified a non...

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Autori principali: Keith, James C, Albert, Leo M, Leathurby, Yelena, Follettie, Max, Wang, Lili, Borges-Marcucci, Lisa, Chadwick, Christopher C, Steffan, Robert J, Harnish, Douglas C
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2005
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1174937/
https://ncbi.nlm.nih.gov/pubmed/15899029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1692
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