Experience-dependent plasticity without long-term depression by type 2 metabotropic glutamate receptors in developing visual cortex

Synaptic depression is thought to underlie the loss of cortical responsiveness to an eye deprived of vision. Here, we establish a fundamental role for type 2 metabotropic glutamate receptors (mGluR2) in long-term depression (LTD) of synaptic transmission within primary visual cortex. Direct mGluR2 a...

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Detalles Bibliográficos
Main Authors: Renger, John J., Hartman, Kenichi N., Tsuchimoto, Yoshiko, Yokoi, Mineto, Nakanishi, Shigetada, Hensch, Takao K.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC117426/
https://ncbi.nlm.nih.gov/pubmed/11805343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.022618799
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