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Implications of CD94 deficiency and monoallelic NKG2A expression for natural killer cell development and repertoire formation

Natural killer (NK) cells are believed to achieve self-tolerance through the expression of self-MHC-specific inhibitory receptors, such as members of the Ly49 and CD94/NKG2 families. Individual Ly49 genes are stochastically expressed by NK subsets and are expressed in a monoallelic fashion, but litt...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Vance, Russell E., Jamieson, Amanda M., Cado, Dragana, Raulet, David H.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2002
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC117397/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11782535/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.022500599
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