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In silico chromosome staining: Reconstruction of Giemsa bands from the whole human genome sequence

Giemsa staining has been used for identifying individual human chromosomes. Giemsa-dark and -light bands generally are thought to correspond to GC-poor and GC-rich regions; however, several experiments showed that the correspondence is quite poor. To elucidate the precise relationship between GC con...

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Bibliographic Details
Main Authors: Niimura, Yoshihito, Gojobori, Takashi
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2002
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC117385/
https://ncbi.nlm.nih.gov/pubmed/11792839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.022437999
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