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Evolution of germ-line signals that regulate growth and aging in nematodes

We show that a signal from the germ line represses growth in the nematode Caenorhabditis elegans. Laser-microbeam ablation of cells that give rise to the germ line causes adults to become giant. Ablation of these cells in self-sterile mutant worms also causes gigantism, suggesting that the germ line...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Patel, Mavji N., Knight, Christopher G., Karageorgi, Constantina, Leroi, Armand M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2002
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC117380/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11805331/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.012511099
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