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Disruption of Centrosome Structure, Chromosome Segregation, and Cytokinesis by Misexpression of Human Cdc14A Phosphatase

In budding yeast, the Cdc14p phosphatase activates mitotic exit by dephosphorylation of specific cyclin-dependent kinase (Cdk) substrates and seems to be regulated by sequestration in the nucleolus until its release in mitosis. Herein, we have analyzed the two human homologs of Cdc14p, hCdc14A and h...

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Autors principals: Kaiser, Brett K., Zimmerman, Zachary A., Charbonneau, Harry, Jackson, Peter K.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC117313/
https://ncbi.nlm.nih.gov/pubmed/12134069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.01-11-0535
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