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On the use of haplotype phylogeny to detect disease susceptibility loci

BACKGROUND: The cladistic approach proposed by Templeton has been presented as promising for the study of the genetic factors involved in common diseases. This approach allows the joint study of multiple markers within a gene by considering haplotypes and grouping them in nested clades. The idea is...

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Detalhes bibliográficos
Main Authors: Bardel, Claire, Danjean, Vincent, Hugot, Jean-Pierre, Darlu, Pierre, Génin, Emmanuelle
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1173100/
https://ncbi.nlm.nih.gov/pubmed/15904492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-6-24
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