Relative quantification of 40 nucleic acid sequences by multiplex ligation-dependent probe amplification

We describe a new method for relative quantification of 40 different DNA sequences in an easy to perform reaction requiring only 20 ng of human DNA. Applications shown of this multiplex ligation-dependent probe amplification (MLPA) technique include the detection of exon deletions and duplications i...

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Detalhes bibliográficos
Main Authors: Schouten, Jan P., McElgunn, Cathal J., Waaijer, Raymond, Zwijnenburg, Danny, Diepvens, Filip, Pals, Gerard
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
Assuntos:
NAR Methods Online
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC117299/
https://ncbi.nlm.nih.gov/pubmed/12060695
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