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c-Myc induces chromosomal rearrangements through telomere and chromosome remodeling in the interphase nucleus
In previous work, we showed that telomeres of normal cells are organized within the 3D space of the interphase nucleus in a nonoverlapping and cell cycle-dependent manner. This order is distorted in tumor cell nuclei where telomeres are found in close association forming aggregates of various number...
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Main Authors: | , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2005
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1172233/ https://ncbi.nlm.nih.gov/pubmed/15983382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407512102 |
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