The hematopoietic factor G-CSF is a neuronal ligand that counteracts programmed cell death and drives neurogenesis

G-CSF is a potent hematopoietic factor that enhances survival and drives differentiation of myeloid lineage cells, resulting in the generation of neutrophilic granulocytes. Here, we show that G-CSF passes the intact blood-brain barrier and reduces infarct volume in 2 different rat models of acute st...

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Autors principals: Schneider, Armin, Krüger, Carola, Steigleder, Tobias, Weber, Daniela, Pitzer, Claudia, Laage, Rico, Aronowski, Jaroslaw, Maurer, Martin H., Gassler, Nikolaus, Mier, Walter, Hasselblatt, Martin, Kollmar, Rainer, Schwab, Stefan, Sommer, Clemens, Bach, Alfred, Kuhn, Hans-Georg, Schäbitz, Wolf-Rüdiger
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2005
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1172228/
https://ncbi.nlm.nih.gov/pubmed/16007267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI23559
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