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A Tetrahymena thermophila ribozyme-based indicator gene to detect transposition of marked retroelements in mammalian cells

We devised an indicator gene for retrotransposition based on an autocatalytic ribozyme element—the Tetrahymena thermophila 23S rRNA group I intron—which can self-splice in vitro and does not require—at variance with nuclear mRNA introns—any specific pathway and cellular component for the completion...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Esnault, Cécile, Casella, Jean-François, Heidmann, Thierry
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC117211/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12034850/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/30.11.e49
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