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Existence of efficient divalent metal ion-catalyzed and inefficient divalent metal ion-independent channels in reactions catalyzed by a hammerhead ribozyme

The hammerhead ribozyme is generally accepted as a well characterized metalloenzyme. However, the precise nature of the interactions of the RNA with metal ions remains to be fully defined. Examination of metal ion-catalyzed hammerhead reactions at limited concentrations of metal ions is useful for e...

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Autori principali: Zhou, Jing-Min, Zhou, De-Min, Takagi, Yasuomi, Kasai, Yasuhiro, Inoue, Atsushi, Baba, Tadashi, Taira, Kazunari
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC117202/
https://ncbi.nlm.nih.gov/pubmed/12034824
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