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Evidence that DNase I hypersensitive site 5 of the human β-globin locus control region functions as a chromosomal insulator in transgenic mice

We have previously reported that DNase I hypersensitive site 5 (5′HS5) of the human β-globin locus control region functions as a chromatin insulator in stable transfection assays. In this report we show that a 3.2 kb DNA fragment containing the entire 5′HS5 region can protect a position-sensitive (A...

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Udgivet i:Nucleic Acids Res
Principais autores: Li, Qiliang, Zhang, Miaohua, Han, Hemei, Rohde, Alex, Stamatoyannopoulos, George
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2002
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC117184/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12034837/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/30.11.2484
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