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Transfer RNA determinants for translational editing by Escherichia coli valyl-tRNA synthetase

Valyl-tRNA synthetase (ValRS) has difficulty differentiating valine from structurally similar non-cognate amino acids, most prominently threonine. To minimize errors in aminoacylation and translation the enzyme catalyzes a proofreading (editing) reaction that is dependent on the presence of cognate...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Tardif, Keith D., Horowitz, Jack
Format: Artigo
Language:Inglês
Published: Oxford University Press 2002
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC117182/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12034843/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/30.11.2538
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