The mechanism of phosphorylation-inducible activation of the ETS-domain transcription factor Elk-1.

Protein phosphorylation represents one of the major mechanisms for transcription factor activation. Here we demonstrate a molecular mechanism by which phosphorylation by mitogen-activated protein (MAP) kinases leads to changes in transcription factor activity. MAP kinases stimulate DNA binding and t...

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Bibliografiske detaljer
Main Authors: Yang, S H, Shore, P, Willingham, N, Lakey, J H, Sharrocks, A D
Format: Artigo
Sprog:Inglês
Udgivet: 1999
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171633/
https://ncbi.nlm.nih.gov/pubmed/10523309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.20.5666
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