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The mechanism of phosphorylation-inducible activation of the ETS-domain transcription factor Elk-1.
Protein phosphorylation represents one of the major mechanisms for transcription factor activation. Here we demonstrate a molecular mechanism by which phosphorylation by mitogen-activated protein (MAP) kinases leads to changes in transcription factor activity. MAP kinases stimulate DNA binding and t...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
1999
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171633/ https://ncbi.nlm.nih.gov/pubmed/10523309 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.20.5666 |
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