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p300 stimulates transcription instigated by ligand-bound thyroid hormone receptor at a step subsequent to chromatin disruption.

We investigate the role of the transcriptional coactivator p300 in gene activation by thyroid hormone receptor (TR) on addition of ligand. The ligand-bound TR targets chromatin disruption independently of gene activation. Exogenous p300 facilitates transcription from a disrupted chromatin template,...

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Main Authors: Li, Q, Imhof, A, Collingwood, T N, Urnov, F D, Wolffe, A P
Format: Artigo
Jezik:Inglês
Izdano: 1999
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171631/
https://ncbi.nlm.nih.gov/pubmed/10523307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.20.5634
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