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Crystal structure of gingipain R: an Arg-specific bacterial cysteine proteinase with a caspase-like fold.
Gingipains are cysteine proteinases acting as key virulence factors of the bacterium Porphyromonas gingivalis, the major pathogen in periodontal disease. The 1.5 and 2.0 A crystal structures of free and D-Phe-Phe-Arg-chloromethylketone-inhibited gingipain R reveal a 435-residue, single-polypeptide c...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
1999
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171614/ https://ncbi.nlm.nih.gov/pubmed/10523290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.20.5453 |
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