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Identification of the catalytic domains and their functionally critical arginine residues of two yeast GTPase-activating proteins specific for Ypt/Rab transport GTPases.

Ypt/Rab proteins constitute the largest subfamily of the Ras superfamily of monomeric GTPases and are regulators of vesicular protein transport. Their slow intrinsic GTPase activity (10(-4)-10(-3) min(-1) at 30 degrees C) has to be accelerated to switch the active to the inactive conformation. We ha...

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Bibliografski detalji
Glavni autori: Albert, S, Will, E, Gallwitz, D
Format: Artigo
Jezik:Inglês
Izdano: 1999
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171592/
https://ncbi.nlm.nih.gov/pubmed/10508155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.19.5216
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