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Active mitochondria surrounding the pancreatic acinar granule region prevent spreading of inositol trisphosphate-evoked local cytosolic Ca(2+) signals.

Agonist-evoked cytosolic Ca(2+) spikes in mouse pancreatic acinar cells are specifically initiated in the apical secretory pole and are mostly confined to this region. The role played by mitochondria in this process has been investigated. Using the mitochondria-specific fluorescent dyes MitoTracker...

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Detaylı Bibliyografya
Asıl Yazarlar: Tinel, H, Cancela, J M, Mogami, H, Gerasimenko, J V, Gerasimenko, O V, Tepikin, A V, Petersen, O H
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1999
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171571/
https://ncbi.nlm.nih.gov/pubmed/10487752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.18.4999
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