Identification by mass spectrometry and functional analysis of novel proteins of the yeast [U4/U6.U5] tri-snRNP.

The 25S [U4/U6.U5] tri-snRNP (small nuclear ribonucleoprotein) is a central unit of the nuclear pre-mRNA splicing machinery. The U4, U5 and U6 snRNAs undergo numerous rearrangements in the spliceosome, and knowledge of all of the tri-snRNP proteins is crucial to the detailed investigation of the RNA...

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Bibliographic Details
Main Authors: Gottschalk, A, Neubauer, G, Banroques, J, Mann, M, Lührmann, R, Fabrizio, P
Format: Artigo
Language:Inglês
Published: 1999
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171528/
https://ncbi.nlm.nih.gov/pubmed/10449419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.16.4535
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