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Cell cycle progression in the presence of irreparable DNA damage is controlled by a Mec1- and Rad53-dependent checkpoint in budding yeast.

We studied the response of nucleotide excision repair (NER)-defective rad14Delta cells to UV irradiation in G(1) followed by release into the cell cycle. Only a subset of checkpoint proteins appears to mediate cell cycle arrest and regulate the timely activation of replication origins in the presenc...

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Bibliografske podrobnosti
Main Authors: Neecke, H, Lucchini, G, Longhese, M P
Format: Artigo
Jezik:Inglês
Izdano: 1999
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171523/
https://ncbi.nlm.nih.gov/pubmed/10449414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.16.4485
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