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Manipulation of outer root sheath cell survival perturbs the hair-growth cycle.

Transgenic mice that overexpress the anti-apoptotic gene bcl-xL under the control of the keratin 14 promoter have significantly shorter hair than non-transgenic littermates. The deficit in hair length correlated with a decrease in the duration of anagen, the growth phase of the hair cycle. A prolong...

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Hlavní autoři: Pena, J C, Kelekar, A, Fuchs, E V, Thompson, C B
Médium: Artigo
Jazyk:Inglês
Vydáno: 1999
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171438/
https://ncbi.nlm.nih.gov/pubmed/10393176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.13.3596
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