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Evidence that free GPI glycolipids are essential for growth of Leishmania mexicana.

The cell surface of the parasitic protozoan Leishmania mexicana is coated by glycosylphosphatidylinositol (GPI)-anchored glycoproteins, a GPI-anchored lipophosphoglycan and a class of free GPI glycolipids. To investigate whether the anchor or free GPIs are required for parasite growth we cloned the...

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Autores principales: Ilgoutz, S C, Zawadzki, J L, Ralton, J E, McConville, M J
Formato: Artigo
Lenguaje:Inglês
Publicado: 1999
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171356/
https://ncbi.nlm.nih.gov/pubmed/10329621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.10.2746
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