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Structure and selectivity in post-translational modification: attaching the biotinyl-lysine and lipoyl-lysine swinging arms in multifunctional enzymes.

The post-translational attachment of biotin and lipoic acid to specific lysine residues displayed in protruding beta-turns in homologous biotinyl and lipoyl domains of their parent enzymes is catalysed by two different ligases. We have expressed in Escherichia coli a sub-gene encoding the biotinyl d...

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Detalhes bibliográficos
Main Authors: Reche, P, Perham, R N
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171349/
https://ncbi.nlm.nih.gov/pubmed/10329614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.10.2673
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