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The Mex67p-mediated nuclear mRNA export pathway is conserved from yeast to human.
Human TAP is an orthologue of the yeast mRNA export factor Mex67p. In mammalian cells, TAP has a preferential intranuclear localization, but can also be detected at the nuclear pores and shuttles between the nucleus and the cytoplasm. TAP directly associates with mRNA in vivo, as it can be UV-crossl...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
1999
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171339/ https://ncbi.nlm.nih.gov/pubmed/10228171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.9.2593 |
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