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Phenotypic switching in Candida albicans is controlled by a SIR2 gene.
We report the cloning of a gene from the human fungal pathogen Candida albicans with sequence and functional similarity to the Saccharomyces cerevisiae SIR2 gene. Deletion of the gene in C. albicans produces a dramatic phenotype: variant colony morphologies arise at frequencies as high as 1 in 10. T...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171338/ https://ncbi.nlm.nih.gov/pubmed/10228170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.9.2580 |
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