A Bub2p-dependent spindle checkpoint pathway regulates the Dbf2p kinase in budding yeast.

Exit from mitosis in all eukaroytes requires inactivation of the mitotic kinase. This occurs principally by ubiquitin-mediated proteolysis of the cyclin subunit controlled by the anaphase-promoting complex (APC). However, an abnormal spindle and/or unattached kinetochores activates a conserved spind...

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Hlavní autoři: Fesquet, D, Fitzpatrick, P J, Johnson, A L, Kramer, K M, Toyn, J H, Johnston, L H
Médium: Artigo
Jazyk:Inglês
Vydáno: 1999
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171325/
https://ncbi.nlm.nih.gov/pubmed/10228157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.9.2424
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