Hsp60 accelerates the maturation of pro-caspase-3 by upstream activator proteases during apoptosis.

The activation of caspases represents a critical step in the pathways leading to the biochemical and morphological changes that underlie apoptosis. Multiple pathways leading to caspase activation appear to exist and vary depending on the death-inducing stimulus. We demonstrate that the activation of...

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Hlavní autoři: Xanthoudakis, S, Roy, S, Rasper, D, Hennessey, T, Aubin, Y, Cassady, R, Tawa, P, Ruel, R, Rosen, A, Nicholson, D W
Médium: Artigo
Jazyk:Inglês
Vydáno: 1999
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171289/
https://ncbi.nlm.nih.gov/pubmed/10205159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.8.2049
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