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Sequence interval within the PEST motif of Bicoid is important for translational repression of caudal mRNA in the anterior region of the Drosophila embryo.

The Drosophila body organizer Bicoid (Bcd) is a maternal homeodomain protein. It forms a concentration gradient along the longitudinal axis of the preblastoderm embryo and activates early zygotic segmentation genes in a threshold-dependent fashion. In addition, Bcd acts as a translational repressor...

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Detalhes bibliográficos
Main Authors: Niessing, D, Dostatni, N, Jäckle, H, Rivera-Pomar, R
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171281/
https://ncbi.nlm.nih.gov/pubmed/10202159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.7.1966
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