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Specific destruction of kinetochore protein CENP-C and disruption of cell division by herpes simplex virus immediate-early protein Vmw110.

Examination of cells at the early stages of herpes simplex virus type 1 infection revealed that the viral immediate-early protein Vmw110 (also known as ICP0) formed discrete punctate accumulations associated with centromeres in both mitotic and interphase cells. The RING finger domain of Vmw110 (but...

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Autori principali: Everett, R D, Earnshaw, W C, Findlay, J, Lomonte, P
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171241/
https://ncbi.nlm.nih.gov/pubmed/10075924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.6.1526
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