EFA6, a sec7 domain-containing exchange factor for ARF6, coordinates membrane recycling and actin cytoskeleton organization.

We have identified a human cDNA encoding a novel protein, exchange factor for ARF6 (EFA6), which contains Sec7 and pleckstrin homology domains. EFA6 promotes efficient guanine nucleotide exchange on ARF6 and is distinct from the ARNO family of ARF1 exchange factors. The protein localizes to a dense...

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Detalhes bibliográficos
Main Authors: Franco, M, Peters, P J, Boretto, J, van Donselaar, E, Neri, A, D'Souza-Schorey, C, Chavrier, P
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171237/
https://ncbi.nlm.nih.gov/pubmed/10075920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.6.1480
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