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Increased neurodegeneration during ageing in mice lacking high-affinity nicotine receptors.
We have examined neuroanatomical, biochemical and endocrine parameters and spatial learning in mice lacking the beta2 subunit of the nicotinic acetylcholine receptor (nAChR) during ageing. Aged beta2(-/-) mutant mice showed region-specific alterations in cortical regions, including neocortical hypot...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171214/ https://ncbi.nlm.nih.gov/pubmed/10064590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.5.1235 |
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